3.0 T MRI对颈动脉粥样硬化斑块成分分析及分型的研究Carotid atherosclerotic plaque composition analysis and classifi cation with 3.0 T MRI
雷云;丁里;任丽香;毕国力;刘达;龚霞蓉;吴昆华;
摘要(Abstract):
目的探讨3.0 T高分辨磁共振成像对颈动脉粥样硬化斑块内部成分检出及斑块稳定性判定的价值。材料与方法 33例颈动脉粥样硬化斑块患者行MRI检查,扫描序列包括三维时间飞跃法(3D-TOF)成像、双翻转T1加权成像、T2加权成像、质子密度(PD)加权成像及增强颈部血管成像,研究、分析斑块内成分及其分型。结果 33例患者中共检出颈动脉粥样硬化斑块63个,分型如下:Ⅰ-Ⅱ型占12.7%,Ⅲ型占27%,Ⅳ-Ⅴ型占19%,Ⅵ型占31.8%,Ⅷ型占9.5%,各型斑块在颈动脉3个部位的分布差异无统计学意义(Fisher确切概率P=0.106);所有检出的颈动脉斑块中稳定斑块共31个,不稳定斑块共32个,二者在是否出现脂质核心(LRNC)、出血(IPH)、血栓形成及纤维帽(FC)破裂方面均有统计学差异(P<0.05),而钙化出现率无统计学差异(P>0.05)。结论 3.0 T高分辨率MRI能识别、区分颈动脉粥样斑块内成分,能鉴别稳定斑块和不稳定斑块,为临床选择治疗方案及疗效评价提供指导。
关键词(KeyWords): 颈动脉;动脉粥样硬化;磁共振成像
基金项目(Foundation): 云南省卫生科技计划项目(编号:2011WS0009)
作者(Authors): 雷云;丁里;任丽香;毕国力;刘达;龚霞蓉;吴昆华;
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