穆靓;杨健;鱼博浪;

• 1:西安交通大学医学院第一附属医院医学影像科

摘要(Abstract)：

缺血缺氧性脑病(HIE)是新生儿危害最大的常见病之一,其病理生理机制及损伤特点复杂。根据脑成熟度、损伤严重程度及持续时间不同,MRI的影像表现各异。本文总结了磁共振弥散加权成像(DWI)及弥散张量成像(DTI)的原理和检查优势。回顾性分析了新生儿HIE的DWI和DTI的各参数变化及其规律。提示DWI能早期检出脑组织缺血缺氧改变的范围,并能一定程度反映细胞分子水平的改变;DTI能连续性反映脑组织轴索、髓鞘细微结构的改变,显示解剖构造与脑功能区域的关联。上述MRI技术的临床应用将为新生儿缺血缺氧性脑病的早期诊断、预后评估、疗效评价提供新的有益支持和保证,具有明显的临床应用优势。

关键词(KeyWords)： 缺血缺氧性脑病,新生儿;弥散加权成像;弥散张量成像;磁共振成像

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金项目资助(30970797)

作者(Authors): 穆靓;杨健;鱼博浪;

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