手法针刺合谷穴得气与脑功能激活关系的探讨Observation of the relation between brain activity and de qi sensation with manual acupuncture at LI4 (Hegu)
陈凤英;沈智威;关计添;肖叶玉;杜丽;吴仁华;
摘要(Abstract)：
目的探讨针灸"得气"与脑功能激活的关系。方法 13例健康右利手受试者,由针灸医师先后进行右手合谷穴"浅表刺激"与传统手法捻针刺激两种任务,利用fMRI-BOLD技术获得脑功能图像,用感兴趣区(ROI)分析方法,比较两种任务下的平均信号变化情况。结果针灸"得气"存在个体差异,相应脑功能的激活情况也有所不同,前额区、丘脑、纹状体、扣带回后部及岛叶功能区随着得气强度的增加而有激活明显的趋势。结论手法针刺合谷穴引起脑功能激活的程度与"得气"情况有关。
关键词(KeyWords)： 功能磁共振成像针灸;合谷穴(LI4);脑
基金项目(Foundation): 国家中医药管理局(02-03JL08);; 广东省自然科学基金(021229)资助
作者(Author): 陈凤英;沈智威;关计添;肖叶玉;杜丽;吴仁华;
Email:
DOI:
参考文献(References)：
- [1]Chen YX,Shen ZW,Xiao YY,et al.Feasibility of fMRI of the human cervical spinal cord using electrical acupoints stimulation.Chin J Magn Reson Imaging,2010,1(6):438441.陈业晞,沈智威,肖叶玉,等.电针刺激穴位的脊髓fMRI初步研究.磁共振成像,2010,1(6):438-441.
- [2]Dai JP,Shen HC,Li SW.MR pulse sequences in the central nervous system:part II.Chin J Magn Reson Imaging,2010,1(4):305-310.戴建平,沈慧聪,李少武.磁共振脉冲序列在中枢神经系统中的应用(二).磁共振成像,2010,1(4):305-310.
- [3]Xiao YY,Wu RH,Pei RQ,et al.Functional MR Imaging(fMRI)of Acupuncture:Observation of Stimulating the Acupoint ST36(zusanli).J Pract Radiol(China),2004,20(2):106-108.肖叶玉,吴仁华,裴仁全,等.针刺足三里穴磁共振功能成像的初步探讨.实用放射学杂志,2004,20(2):106-108.
- [4]Hui KK,Liu J,Makris N,et al.Acupuncture modulates the limbic system and subcortical gray structures of the human brain:evidence from fMRI studies in normal subjects.Hum Brain Mapping,2000,9(1):3-25.
- [5]Wang GB,Shao GR.Advances of fMRI Study on Acupuncture Stimulation in Human Brain.J Pract Radiol(China),2006,22(8):1002-1007.王光彬,邵广瑞.针刺磁共振脑功能成像研究进展.实用放射学杂志,2006,22(8):1002-1007.
- [6]Hu KM,Zhu MJ,Hennig J.Relationship between cerebral function and Kuangming and Taichong acupoints detected with functional MRI.Chin J Clin Rehabil,2005,9(9):203209.
- [7]Wu MT,Sheen JM,Chuang KH,et al.Neuronal specificity of acupuncture response:An fMRI study with electroacupuncture.NeuroImage,2002,16(4):1028-1037.
- [8]Liu WC,Feldman SC,Cook DB,et al.fMRI study of acupuncture-induced periaqueductal gray activity in humans.NeuroReport,2004,15(12):1937-1940.
- [9]Wang W,Li KC,Shan BC,et al.Study of acupuncture point Liv3with functional MRI.Chin J Radiol,2006,40(1):2935.王葳,李坤成,单保慈,等.针刺太冲穴的脑功能MRI研究.中华放射学杂志,2006,40(1):29-35.
- [10]Xu JY,Yan B,Wang FQ,et al.Study of brain function imaging induced by acupuncture at acupoint LI4(Hegu).Chin J Rehabil Theory Pract,2005,11(10):832-833.许建阳,闫镔,王发强,等.针刺合谷穴对脑功能成像的研究.中国康复理论与实践,2005,11(10):832-833.
- [11]Chen FY,Wu RH.Functional MR imaging on acupuncture effects:current status and prospects.Med Imaging(China),2006,16(12):1298-1301.陈凤英,吴仁华.针灸效应磁共振研究现状与前景.医学影像学杂志,2006,16(12):1298-1301.