谢宗源;徐香玖;黄刚;周星;马小梅;王治民;铁萍;张庆;

• 1:宁夏医科大学
• 2:甘肃省人民医院放射科
• 3:甘肃中医学院

摘要(Abstract)：

目的探讨直肠癌动态对比增强磁共振成像(DCE-MRI)参数的特点及其与病理分化程度、Dukes分期的关系。材料与方法对56例经病理证实为直肠癌患者的DCE-MRI图像进行回顾性分析,绘制时间-信号强度曲线(TIC)、构建Ktrans、Ve、Kep参数图,并分析TIC、Ktrans、Ve、Kep值的特点及其与肿瘤分化程度、Dukes分期的相关性。结果将直肠癌及肿瘤周围正常直肠壁的TIC分为3种类型,其中Ⅱ型8例,Ⅲ型48例,肿瘤周围正常直肠壁Ⅰ型为41例、Ⅱ型15例。直肠癌的Ktrans值随肿瘤分化程度减低,Dukes分期增加而升高(P值均<0.01);Ve、Kep值差异无统计学意义。结论 DCE-MRI能反映肿瘤内部的血流动力学情况,TIC及Ktrans值与直肠癌的病理分化程度、Dukes分期具有一定相关性,TIC及Ktrans值可能用于评价直肠癌的恶性程度。

关键词(KeyWords)： 直肠癌;磁共振成像;动态增强;时间-信号强度曲线;容量转移常数

Abstract:

Keywords:

基金项目(Foundation): 甘肃省卫生行业科研计划基金项目(编号:GSWST2013-01)

作者(Authors): 谢宗源;徐香玖;黄刚;周星;马小梅;王治民;铁萍;张庆;

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