邓娟;王俊;李昇霖;刘显旺;薛彩强;周俊林;

• 1:兰州大学第二医院放射科
• 2:兰州大学第二临床医学院
• 3:甘肃省医学影像重点实验室

摘要(Abstract)：

目的探讨MR常规检查联合扩散加权成像(diffusion-weighted imaging,DWI鉴别诊断不典型肝脓肿与肝内胆管细胞癌(intrahepatic cholangiocarcinoma,ICC)的价值。材料与方法回顾性分析19例ICC和19例不典型肝脓肿患者的MR图像,观察两组间病灶MR征象及病灶边缘实性部分的平均表观扩散系数(mean apparent diffusion coefficient,ADCmean)值及相对表观扩散系数(relative ADC,rADC)值的差异。采用独立样本t检验及χ2检验分析两组MR征象及ADC值的差异。结果 ICC与不典型肝脓肿在动脉期断环征、肝组织异常灌注、肝包膜的皱缩方面差异有统计学意义(P<0.05)。ICC病灶边缘实性成分ADCmean值为(0.84±0.14)×10-3mm2/s,rADC值为(0.70±0.12);肝脓肿边缘实性部分的ADCmean值为(1.04±0.10)×10-3mm2/s,rADC值为(0.95±0.05),两组间差异有统计学意义(P<0.001)。ADCmean值、rADC值ROC曲线下面积分别为0.832、0.964,ADCmean值以0.86×10-3mm2/s为截断值,鉴别两者的敏感度、特异度分别为100%和63.2%,rADC以0.83为截断值,鉴别两者的敏感度、特异度分别为100%和84.2%。结论 MR常规检查联合DWI有助于鉴别ICC与不典型肝脓肿。

关键词(KeyWords)： 胆管细胞癌;肝脓肿;磁共振成像;扩散加权成像;表观扩散系数

Abstract:

Keywords:

基金项目(Foundation): 兰州市人才创新创业项目(编号：2016-RC-58)~~

作者(Author): 邓娟;王俊;李昇霖;刘显旺;薛彩强;周俊林;

Email:

DOI:

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