李松涛;汪文胜;周全;邓达标;黄海涛;梁倩雯;成丽娜;

• 1:广东三九脑科医院影像中心
• 2:暨南大学附属第一医院医学影像中心

摘要(Abstract)：

目的分析中枢神经系统神经母细胞瘤的影像学特点,探讨CT及MRI对该病的诊断价值。材料与方法对6例经手术病理证实的中枢神经系统神经母细胞的影像资料进行回顾性分析。结果男5例,女1例,年龄3~24岁,平均13.8岁。幕上3例,分别位于颞极区1例,颞枕叶及顶叶各1例;幕下四脑室内和桥脑各1例,另1例跨小脑天幕。肿块呈囊实性2例,实性为主4例。MRI表现肿瘤实性部分呈等或稍长T1、T2信号,FLAIR序列呈等、稍高信号;囊性部分呈长T1、长T2信号,FLAIR序列呈低信号;增强扫描后,2例强化不明显,4例肿瘤实性部分呈明显强化,肿块边界较清楚,瘤周水肿较轻。CT表现肿瘤实性部分呈等、稍高密度,其内可见钙化,囊性部分呈低密度。结论中枢神经系统神经母细胞瘤影像表现有一定的特点,根据肿瘤部位、边界、信号(或密度)、水肿、增强等特点有助于该病的诊断和鉴别诊断。

关键词(KeyWords)： 神经母细胞瘤;体层摄影术,X线计算机;磁共振成像

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 李松涛;汪文胜;周全;邓达标;黄海涛;梁倩雯;成丽娜;

Email:

DOI:

参考文献(References)：

• [1]Yang XJ,Jiang T.Unscramble《Classification of central nervous system tumors in WHO(2016Y)》.Chin J Ner Ment Dis,2016,42(6):321-329.杨学军,江涛.解读《世界卫生组织中枢神经系统肿瘤分类(2016年)》.中国神经精神疾病杂志,2016,42(6):321-329.
• [2]Rubinstern LJ.Embryonal central neuroepithelial tumors and their differentiating potential:a cytogenetic v-iew of a complex neurooncological problem.J Neurosurg,1985,62(6):795-805.
• [3]Qiao ZW,Li GP,Pa ME,et al.Distinguishing neuroblastoma invading the kidney from nephroblastoma e-valuation on computed tomography.Zhong Hua Fang She Xue Za Zhi,2005,39(7):747-750.乔中伟,李国平,帕米尔,等.儿童腹膜后成神经细胞瘤侵犯肾脏与肾母细胞瘤的鉴别诊断.中华放射学杂志,2005,39(7):747-750.
• [4]Huang WQ,Pathology of nerves tumor.2nd ed.Beijing:Military Medical Science Press,2001:443-449.黄文清.神经肿瘤病理学.2版.北京:军事医学科学出版社,2001:443-449.
• [5]Riley RD,Heney D,Jones DR,et al.A systematic review of molecular and biological tumor markers in n-euroblastoma.Clin Cancer Res,2004,10(1):4.
• [6]Wan SH,Zhang XL,Xiong W,et al.MRI manifestations of primary cerebral neuroblastoma.Chin J Med Imaging Technol,2006,22(12):1808-1811.宛四海,张雪林,熊伟,等.原发性中枢神经母细胞瘤的MRI表现.中国医学影像技术,2006,22(12):1808-1811.
• [7]Zheng HW,Qi PH,Xue P,et al.CTand MRI featuresand pathological findings of CNS Neuroblastomas.J Clin Radiol,2013,32(2):284-287.郑红伟,祁佩红,薛鹏,等.中枢系统神经母细胞瘤的影像表现及其病理分析(附4例报告).临床放射学杂志,2013,32(2):284-287.
• [8]Li WH,Jin HM,Zhang ZD.CT and MRI and pathology analysis of neuroblastoma in children.Radiol Practice,2005,20(1):21-23.李文华,金惠民,张忠德.儿童脑神经母细胞瘤的CT、MRI和病理分析.放射学实践,2005,20(1):21-23.
• [9]Peng WS,Zhang CQ,Liu YP.et al.MRI diagnosis analysis of children's brain neuroblastoma.Chin J Modern Med,2013,15(6):17-19.彭望书,张超群,刘益平,等.儿童大脑神经母细胞瘤MRI诊断分析.中国现代医药杂志,2013,15(6):17-19.
• [10]Chu CM,Rasalkar DD,Hu YJ,et al.Clinical presentations and imaging findings of neuroblastoma.beyond abdominal mass and a review of imaginf algorithm.Br J Radiol,2011,84(997):81-91.
• [11]Xiao H.Imaging of neruoblastoma in fouth ventricle:a case.J Pract Med,2013,29(17):2935-2936.肖海.第四脑室神经母细胞瘤1例.实用医学杂志,2013,29(17):2935-2936.
• [12]Davis PC,Wichman RD,Takei Y,et al.Primary cerebral neuroblastoma:CT and MR findings in 12 cases.AJR Am J Roentgenol,1990,154(4):831.
• [13]Xu L,Cheng GX,Li XN.MR imaging features and misdiagnosis analysis of intracranial pleomorphic xanthoastrocytoma.Chin J Med Imaging Technol,2015,31(2):201-205.徐露,成官迅,李学农.颅内多形性黄色星形细胞瘤的MRI表现及误诊分析.中国医学影像技术,2015,31(2):201-205.
• [14]Wu YQ,Lin Q,Lan YH,et al.Glioblastoma multi-mode MRI manifestations and pathological histology foundation.Chin J Magn Reson Imaging,2013,4(3):196-200.吴裕强,林祺,兰玉华,等.胶质母细胞瘤多模式MRI表现及其病理组织学基础.磁共振成像,2013,4(3):196-200.
• [15]Yuan T,Ding FF,Quan GM,et al.Correlation study of arterial spin labeling and dynamic susceptibility-weighted contrast enhanced MR imaging in the blood flow of astrocytoma.Radiol Practice,2015,9(30):922-927.袁涛,丁芳芳,全冠民,等.3D-ASL与DSC对星形细胞瘤血流灌注评估的相关性研究.放射学实践,2015,9(30):922-927.
• [16]Chen R,Peng DC,Hu ZL,et al.Differences in MRI findings between intracranial hemangiop ericytoma and angionmatous meningioma.Chin J Magn Reson Imaging,2016,7(3):173-179.陈荣,彭德昌,胡祖力,等.颅内血管周细胞瘤与血管瘤型脑膜瘤的磁共振成像征象对比分析.磁共振成像,2016,7(3):173-179.