雷杜晶;吴富淋;余波;陈秋雁;江敏;

• 1:福建医科大学附属宁德市医院放射科

摘要(Abstract)：

目的探讨颈内动脉系统性短暂性脑缺血发作(transient ischemic attack,TIA)患者出现液体衰减反转恢复序列血管高信号征(fluid-attenuated inversion recovery vascular hyperintensities,FVH)与其短期内继发脑梗死是否具有相关性。材料与方法回顾性分析2010年1月至2019年3月168例在我院首诊为TIA而MRI上未见到梗死灶并持续进行复查的患者MRI图像及临床资料,应用多因素回归分析法分析FVH、颈内动脉粥样硬化(internal carotid atherosclerosis,ICAS)等是否为TIA患者短期内发生脑梗死的危险因素。结果 168例符合条件的患者中,30例患者(17.86%)具有单侧FVH,45例患者(26.79%)发生短期内脑梗死[出现扩散加权成像(diffusion-weighted imaging,DWI)高信号],据此分为R-DWI [+]组和R-DWI [-]组。多因素回归分析显示,FVH (aOR=0.079,95%CI=0.020～0.310,P<0.001)、ICAS (aOR=0.257,95%CI=0.082～0.810,P<0.001)均为R-DWI组的危险相关因素。即使在校正了FVH×ICAS(用以消除FVH和ICAS的交互性)后,FVH仍表现为R-DWI [+]的独立相关因素。结论 FVH是TIA患者短期内发生脑梗死的独立相关因素。

关键词(KeyWords)： 液体衰减反转恢复序列;血管高信号征;短暂性脑缺血发作;磁共振成像;卒中

Abstract:

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基金项目(Foundation): 福建省自然科学基金(编号：2017J01167);; 宁德市医技提升科研项目(编号：20170103);; 福建医科大学启航基金项目(编号：2016QH099)~~

作者(Author): 雷杜晶;吴富淋;余波;陈秋雁;江敏;

Email:

DOI:

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