干燥综合征的颌下腺MRI表现MRI features of the submandibular gland in Sj?gren syndrome
纪权书;丁长伟;王月;
摘要(Abstract)：
目的探讨干燥综合征(Sj?gren's syndrome,SS)患者颌下腺MRI的表现及诊断效能。材料与方法收集确诊为SS的31例女性患者和15例健康志愿者的颌下腺MRI图像。观察T1WI、T2WI及抑脂T2WI图像,并对患者颌下腺进行脂肪信号分级。测量受试者双侧颌下腺体积,并观察两组体积改变。结果所有患者均呈双侧颌下腺信号不均改变,T1WI和T2WI均为多发弥漫分布脂肪信号,抑脂T2WI呈低信号。在62个腺体中,常规MRI检出病变50个,无假阳性结果。对照组15例30个颌下腺腺体内未见脂肪信号,脂肪信号分级为0级。颌下腺脂肪信号分级的敏感度为80.7%,阳性预测值为100%,特异度为100%。颌下腺脂肪信号分级的曲线下面积(area under curve,AUC)为0.903。病例组颌下腺体积小于对照组体积(P<0.05),病例组非0级颌下腺体积小于0级颌下腺体积(P<0.05)。病例组颌下腺体积与脂肪信号分级相关性较差(r=-0.102,P>0.05),且结果无统计学意义。结论常规颌下腺MRI检查可以作为辅助诊断SS的影像学检查之一。
关键词(KeyWords)： 干燥综合征;颌下腺;磁共振成像
基金项目(Foundation): 辽宁省自然科学基金(编号：20170541045)~~
作者(Author): 纪权书;丁长伟;王月;
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